Create roadmap diagrams for spatial workshop

[sjspielman]

Similar to the roadmap diagrams we have for intro and advanced scRNA-seq, we should have analogous diagrams for spatial (single-sample analysis only at this time).

Miscellaneous thoughts I have that aren't fleshed out yet but want to record them to flesh out soon!

• I'd expect a diagram to have import, filtering, normalization and then a branch either to reduced dimension & clustering or to SVGs, or to deconvolution
  • That said deconvolution takes in raw counts, not logcounts, so be careful to not mislead here
• So we want a separate diagram for low-res vs high-res techologies? Similarly, within high-res we are now introducing both image-based and seq-based techs. Are these separate or not? I imagine there is definitey at least one separate item here - maybe a high-res with two subdiagrams...

This may be broken into subissues.

[allyhawkins]

So we want a separate diagram for low-res vs high-res techologies? Similarly, within high-res we are now introducing both image-based and seq-based techs. Are these separate or not? I imagine there is definitey at least one separate item here - maybe a high-res with two subdiagrams...

Much of the initial steps here are the same, so I think we could have a shared section and then a high-res and low-res section. The low-res section would include deconvolution and the high-res section would include cell type annotation and neighborhood analysis.

At least this would work for an overall roadmap. We might want a detailed roadmap that shows actual functions too and that would have to be separate.

[sjspielman]

Started making something here - just a Visium overview roadmap for now. I'm using green for this one, since it's my favorite color. Am open to suggestions for different greens though! 😉

https://docs.google.com/presentation/d/194GCO8WB2uqT4LYRtUNgS15M5IxBN8PhGW3GjaWsqww/edit?usp=sharing