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CnvTranslator: c. HGVS inputs should be converted to n. before building SequenceLocation

bugSomething isn't workingSomething isn't working

Status: Open.

#629 In ga4gh/vrs-python;

· theferrit32 opened on Apr 17, 2026

HgvsTools.is_intronic misses intronic r. (RNA) variants

bugSomething isn't workingSomething isn't working

Status: Open.

#628 In ga4gh/vrs-python;

· theferrit32 opened on Apr 17, 2026

Add Adjacency Translator

enhancementNew feature or requestNew feature or request

Status: Open.

#627 In ga4gh/vrs-python;

· korikuzma opened on Apr 17, 2026

Replace DataProxy.get_metadata with get_length and get_aliases

Status: Open.

#624 In ga4gh/vrs-python;

· theferrit32 opened on Apr 14, 2026

Rename translate from/to

Status: Open.

#623 In ga4gh/vrs-python;

· korikuzma opened on Apr 13, 2026

Translator should support HGVS splice variants

Status: Open.

#612 In ga4gh/vrs-python;

· korikuzma opened on Feb 3, 2026

Add translator support for uncertain range HGVS expressions

Status: Open.

#609 In ga4gh/vrs-python;

· theferrit32 opened on Jan 23, 2026

Subclass of AbstractVcfAnnotator can decide to abort annotation

Status: Open.

#605 In ga4gh/vrs-python;

· ehclark opened on Jan 2, 2026

Investigate integrating with DuckDB/Object storage vs. postgres requirement

v3Issues targeting a v3.x.x release of vrs-pythonIssues targeting a v3.x.x release of vrs-python

Status: Open.

#600 In ga4gh/vrs-python;

· david4096 opened on Dec 17, 2025

Integrate seqrepo builds from github actions to vrs-in-a-box

Status: Open.

#599 In ga4gh/vrs-python;

· david4096 opened on Dec 17, 2025

RLE_SEQ_LIMIT should be configurable

Status: Open.

#598 In ga4gh/vrs-python;

· korikuzma opened on Dec 15, 2025

Add a function to recursively add IDs to a VRS object and every contained identifiable object

enhancementNew feature or requestNew feature or request

Status: Open.

#596 In ga4gh/vrs-python;

· jsstevenson opened on Dec 4, 2025