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Bio Sequence Alignment

This project implements pairwise sequence alignment algorithms used in bioinformatics to compare DNA, RNA, or protein sequences.

  • Needleman–Wunsch (1970) → Global alignment (full sequences)
  • Smith–Waterman (1981) → Local alignment (best subsequences)

Both rely on dynamic programming with configurable match, mismatch, and gap scores.


Features

  • Global and local alignment
  • Multiple optimal local alignments
  • Alignment object (aligned seqs, indices, score)
  • Pytest test suite with CSV test cases

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Global & Local Alignment in Python (Needleman-Wunsch, Smith-Waterman)

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