Skip to content

docs: fix stale 500K hypermutation threshold in cancer report QC table - #104

Open
qclayssen wants to merge 2 commits into
mainfrom
fix/hypermutation-threshold-450k
Open

docs: fix stale 500K hypermutation threshold in cancer report QC table#104
qclayssen wants to merge 2 commits into
mainfrom
fix/hypermutation-threshold-450k

Conversation

@qclayssen

@qclayssen qclayssen commented Aug 5, 2026

Copy link
Copy Markdown
Contributor

Summary

  • The cancer report QC summary table said samples are flagged hypermutated above 500K SNVs. The actual bolt safety threshold is 450,000 (MAX_SOMATIC_VARIANTS, sash ADR-001), so the doc text was stale.
  • Fixes the wording in inst/rmd/umccrise/cancer_report.Rmd to say 450K instead of 500K.

Context: sash 0.7.1 + bolt 0.3.2 validation (biodaily#227) surfaced this discrepancy while re-confirming the hypermutator handling path. See UMCCR Slack thread: https://umccr.slack.com/archives/C025TLC7D/p1773817713888619?thread_ts=1773276509.471689&cid=C025TLC7D

Test plan

  • Docs-only change — no functional code paths affected
  • Confirm rendered cancer report QC table shows "450K" text correctly

qclayssen added 2 commits May 25, 2026 09:55
Regression guard: 563f946 accidentally re-introduced required=TRUE,
causing crashes on samples without DRAGEN HRD files.
Actual bolt safety threshold is 450,000 (MAX_SOMATIC_VARIANTS, ADR-001),
not 500K.
@qclayssen qclayssen self-assigned this Aug 7, 2026

@pdiakumis pdiakumis left a comment

Copy link
Copy Markdown
Member

Choose a reason for hiding this comment

The reason will be displayed to describe this comment to others. Learn more.

Thanks, LGTM

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment

Labels

None yet

Projects

None yet

Development

Successfully merging this pull request may close these issues.

2 participants